CLINICAL UTILITY OF MONITORING CLINICAL USEFULNESS OF HOLTER ELECTROCARDIOGRAM While the emergence of Holter dates back to 1961, the first article reporting the use of this monitoring in veterinary medicine does not appear until 1991 (Ambulatory electrocardiography in dogs.Hall LW et al Vet Rec.) The first records were too bulky and heavy and could only be used in large breeds. But technological advances and the advent of digital recorders have reduced the size and weight to the point that their use is feasible even in the case of cats as has already been published. 22, 23
Several decades of clinical experience in dogs and cats have shown that Holter monitoring is a cost-effective tool for the diagnosis and evaluation of heart rhythm disorders, aid in risk stratification of sudden death in cardiomyopathy of Doberman and Boxer, and evaluation of treatment-10
antiarrítmicos.2
DIRECTIONS REGISTRATION A registration HOLTER Holter
is indicated in many clinical situations, typically in the detection and assessment of the severity of supraventricular or ventricular tachyarrhythmias as well as bradyarrhythmias. Can be used for:
1. Assess the complexity and frequency of cardiac arrhythmias detected during the resting ECG or auscultation.
2. To evaluate the efficacy of pharmacological treatment.
3. Help determine the differential diagnosis in dogs with syncope and presyncope, when cardiac rhythm disturbances are not evident during auscultation or resting ECG.
4. It is useful as a screening test for cardiomyopathy in Doberman and Boxer.
5. Determine the ventricular rate in atrial fibrillation dogs before and after treatment.
6. To assess the functional integrity of the artificial pacemaker.
A series of articles in the veterinary medical literature have described the use of Holter recordings for some of these indications. 2 ,3,7-9 ,11-16
1) assessment of the severity of the arrhythmia
When a veterinarian identifies a change in heart rhythm on auscultation in asymptomatic dogs in the resting ECG EV occasionally observed, it is not appropriate to assume that the arrhythmia is benign. A resting ECG records only a brief sample in time, but the arrhythmia is often more or less severe than estimated in a short ECG recording. February 10
Although the cause of an arrhythmia is often of greater prognostic value than the type of arrhythmia or complexity, ventricular tachycardia at a rate exceeding 250 beats / min, is always concern. Lethal ventricular tachycardia occurs in dogs at a rate exceeding 300 beats / min. At this rate, ventricular tachycardia can degenerate into ventricular fibrillation. 7 -9 ,11-13. Dogs with subaortic stenosis are an exception because the ventricular tachycardia can degenerate into ventricular fibrillation at rates even as low as 170 beats / min. As all dogs with subaortic stenosis should be evaluated by Holter for the presence (and severity) of arritmias.2 ,3,7-11, 13,14,16
2) To evaluate the effectiveness
antiarrhythmic therapy has already been shown in veterinary the greater sensitivity of Holter monitoring compared to conventional ECG to detect arrhythmias espontáneas.2-10 These arrhythmias often have a large inherent variability and often require a Holter study before and after treatment to determine whether medical therapy is having proarrhythmic effects, antiarrhythmic or if no effectiveness.3, 12.18.
The severity of ventricular tachyarrhythmias in a period of 24 to 48 hours vary considerablemente.2, 10. Sometimes arrhythmias appear to be well controlled when the patient is at rest, only to become severe during exercise or excitement, or even for no reason. 3, 8,13,15,16.
Holter analysis is the most accurate noninvasive method to verify the effectiveness of pharmacological treatment in veterinary patients.
3) Diagnosis of the cause of syncope when heart rhythm disturbances are not evident
Syncope due to cardiac arrhythmias is common in dogs. May be due to bradycardia, ventricular tachycardia, or fast, less frequently, rapid supraventricular tachycardia. The Holter can be a useful diagnostic test in patients with syncope and / or episodic weakness when the cause of syncope is not evident on an ECG tradicional.3, 11
neurocardiogenic syncope
neurocardiogenic syncope is common in geriatric dogs breeds pequeñas.19 In these patients apart from the bradycardia during syncope, heart rate and rhythm are usually normales.19 The Holter monitor to document the heart rhythm during syncope .
neurocardiogenic syncope is also a cause of syncope in some large breed dogs, especially Boxers and Golden Retrievers.20 Some normal dogs experiencing intense emotional episodes reflex bradycardia by stimulation adrenérgica.20 When there cardiomyopathy these dogs have normal echocardiograms and little or no EVs on ECG superficie.20 Boxers with cardiomyopathy may also experience bradycardia neurocardiogenic but may be accompanied by ventricular tachyarrhythmias of variable severity with or without abnormalities ecocardiográficas.20 Differentiation of the cause of syncope has important therapeutic implications.
other hand we have seen that the Doberman with cardiomyopathy may suffer fainting from excitement due to transient neurocardiogenic bradycardia. 11 In fact in Doberman, neurocardiogenic bradycardia with syncope is a marker of cardiomiopatía.11 Holter monitoring is essential to differentiate between neurocardiogenic syncope and those caused by ventricular tachycardia. 20
Bradycardia Sick sinus syndrome.
all bradyarrhythmias are not neurally mediated. Sick sinus syndrome is usually associated with the Cocker Spaniel, Miniature Schnauzer and West Highland White Terrier. When the bradycardia is the cause of syncope syndrome usually becomes evident in a resting ECG. The atrioventricular conduction block (AV) are generally advanced due to the degeneration of pathways. AV conduction blocks serious enough to cause syncope are usually evident in a resting ECG.
Ventricular arrhythmias and myocardial disease.
Patients with myocardial disease may present with syncope secondary to ventricular tachycardia. In patients with suspected this type of syncope and, if the ECG is not documented ventricular tachycardia, Holter monitoring is particularly suitable.
Atrial fibrillation secondary to advanced heart disease.
Syncope and episodic weakness may also occur after the onset of atrial fibrillation in dogs with advanced heart disease. In these patients, atrial fibrillation is evident in a resting ECG. It is assumed that poor cardiac function, loss of atrial contraction, and rapid, irregular rhythm derived from the arrhythmias produced a marked decrease in cardiac output, leading to syncope. However, in dogs with cardiomyopathy and atrial fibrillation, syncope can also be caused by paroxysmal ventricular tachycardia. The Holter can be a useful tool in the diagnosis of syncope in which the cause is not obvious and can be either the result of atrial fibrillation as a tachycardia ventricular.3 ,11-16
Others.
Holter monitoring can help detect and treat arrhythmias hereditary Pastor German and differential diagnosis of Labradors with syncope associated with exercise. Also present is the most sensitive method to diagnose arrhythmogenic right ventricular dysplasia in both dogs and cats. 27
4) Screening in Doberman Pinscher and Boxer for cardiomyopathy
Cardiomyopathies are common in Doberman and Bóxers.7-9, 12.16 Owners and breeders of these breeds are becoming aware of the high incidence of these problems and are increasingly looking for more, screening of veterinarians. The more premature marker of cardiomyopathy in these races is the total number of EVs gained per record Holter.8, 9,15,16
is recommended, therefore, perform echocardiography and Holter monitoring once a year to all apparently healthy adult Doberman and Boxer.
5) Determination of ventricular rate in atrial fibrillation Atrial fibrillation
one of the most common arrhythmia in dogs and is usually associated with advanced heart disease. Often when detected by traditional ECG, atrial fibrillation is presented as a persistent heart rate, rapid and irregular. The rate control rather than trying to control the pace, is a common treatment strategy for dogs with atrial fibrillation.
When dogs are examined in the hospital, particularly during immobilization for diagnostic testing, the sympathetic nervous system activity usually increases. This sympathetic activation decreases the refractory period of AV node tissue and increases its conductivity. For this reason, when a resting ECG is performed on a dog being treated for atrial fibrillation, ventricular response rate is higher when the patient is in the quiet of their surroundings habitual.21
The Holter monitoring in the home allows the accurate measurement of heart rate and their characteristics over a period of 24 hours in a natural environment and thus assess the effectiveness of treatment. There is evidence that in most patients, heart rate in the home environment is significantly slower than in the hospital.21
6) Evaluation of the functional integrity of artificial cardiac pacemakers
In Dogs with permanent artificial pacemaker, regularly confirmed normal pacemaker function. Holter monitoring can also provide information on pacemaker function, as the quantification of normal rate versus time of accelerated rate, sensitivity function of the speed of response to activity levels and the adequacy of the inhibition of spontaneous ectopic activity. Due to time constraints during the routine examination of hospital visits and limited capacity to store records pacemaker abnormal ECG, a Holter monitor may facilitate the diagnosis of pacemaker malfunction in recording the patient's rhythm over 24 hours or more daily activities.
TECHNICAL
Holter recorders are available with three to five electrodes. Five electrodes recorders have a higher sensitivity to differentiate artifacts from cardiac arrhythmias and differences of ESVs EVs.
However, the three-electrode Holter recorders are easy to implement and usually provide sufficient data
and carefully applying the electrodes ensuring you can almost always get high quality records. It is essential to have a good contact between electrodes and skin. To do this, you shave the hair on the binding sites of the electrodes. When the electrode-skin contact is firm and it's all well wrapped to prevent movement of the electrode, you get a high quality recording both during tranquil periods and as assets. Even vigorous activity is not usually associated with excessive artifacts. The
Holter placement requires a shave both sides of the chest, just caudal to the elbow (about the heart). Cropped areas may be relatively small enough to accommodate 5 or 7 patches (2 on one side, 3 on the other). The areas where the adhesive pads will be properly degreased with alcohol.
After fixing the electrodes are plugged and register them with a cohesive bandage that ensures your contact during the recording.
is essential that the owner keep a diary of the activities of the dog during the registration period. This journal should be attached to the examination for a correct interpretation.
OUTLOOK
Holter monitoring has been established as reliable method for detection and quantification of arrhythmias but is now starting to delve into both the Holter as a tool for assessing the integrity of the nervous system self as for the prediction of sudden death and there are publications that have evaluated the variability of heart rate 24 26, the T wave microalternancia or the phenomenon of turbulence. 25
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22. 24-Hour Holter Monitoring of Healthy Cats at Home with a New Light Holter Recorder. 17th ECVIM-CA Congress, 2007
23. Twenty-four hour Holter monitoring of unsedated healthy cats in the home environment. J Vet Cardiol. 2009 Jun;11(1):17-22
24. Assessment of heart rate variability in Boxers with arrhythmogenic right ventricular cardiomyopathy. J Am Vet Med Assoc. 2004 Feb 15; 224 (4) :534-7
25. Heart Rate Turbulence in Healthy Dogs - Preliminary Study, 19th Congress ECVIM-CA, 2009
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27. Arrhythmogenic right ventricular cardiomyopathy in two cats. J Small Anim Pract. 2005 Mar; 46 (3) :151-6.